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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-307
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-30
filingDate 2019-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110068604-B
titleOfInvention Novel electrochemical sensor for rapidly detecting trace phosphoprotein by using porous hafnium oxide nano thin layer and preparation method and application thereof
abstract The invention discloses a novel electrochemical sensor for quickly detecting trace phosphoprotein by using a porous hafnium dioxide nano thin layer. The invention has the advantages that: 1) the properties of high conductivity, large specific surface area and the like of the gold nanoparticles are skillfully utilized, the gold nanoparticles are mainly utilized to increase the surface dispersibility of the electrode, and a certain electrostatic adsorption effect is achieved on metal oxidation, so that good conditions are provided for the next polymerization of the hafnium dioxide nanoparticles, and the defect that metal oxide is difficult to polymerize on the surface of the glassy carbon electrode is overcome; 2) the Lewis acidity and basicity of the novel metal oxide hafnium dioxide are ingeniously utilized, so that the phosphate groups are subjected to specific reversible adsorption and release on the surface of the novel metal oxide hafnium dioxide, the online enrichment and detection of phosphoprotein are realized, and the interference of non-phosphoprotein is overcome.
priorityDate 2019-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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