http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110066351-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2203-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 |
filingDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110066351-B |
titleOfInvention | Alkylated cyclodextrin compositions and methods of making and using the same |
abstract | The present invention relates to alkylated cyclodextrin compositions and methods of making and using the same. Specifically, the present invention relates to a process for preparing an alkylated cyclodextrin composition comprising an alkylated cyclodextrin, comprising: (a) mixing a cyclodextrin with an alkylating agent to form a reaction environment comprising an alkylated cyclodextrin, one or more undesirable components, and one or more drug-degrading impurities; (b) performing one or more separations to remove the one or more undesirable components from the reaction environment, thereby forming a partially purified solution comprising the alkylated cyclodextrin and the one or more drug-degrading impurities, wherein the one or more separations is ultrafiltration, diafiltration, centrifugation, extraction, solvent precipitation, or dialysis; (c) treating the partially purified solution with phosphate-free activated carbon having a residual conductivity of 10 μ S or less and producing the alkylated cyclodextrin; and (d) measuring the chloride level of the alkylated cyclodextrin composition; wherein the chloride level is 0.07% (w/w) or less. |
priorityDate | 2012-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.