http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110066351-B

Outgoing Links

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69
filingDate 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110066351-B
titleOfInvention Alkylated cyclodextrin compositions and methods of making and using the same
abstract The present invention relates to alkylated cyclodextrin compositions and methods of making and using the same. Specifically, the present invention relates to a process for preparing an alkylated cyclodextrin composition comprising an alkylated cyclodextrin, comprising: (a) mixing a cyclodextrin with an alkylating agent to form a reaction environment comprising an alkylated cyclodextrin, one or more undesirable components, and one or more drug-degrading impurities; (b) performing one or more separations to remove the one or more undesirable components from the reaction environment, thereby forming a partially purified solution comprising the alkylated cyclodextrin and the one or more drug-degrading impurities, wherein the one or more separations is ultrafiltration, diafiltration, centrifugation, extraction, solvent precipitation, or dialysis; (c) treating the partially purified solution with phosphate-free activated carbon having a residual conductivity of 10 μ S or less and producing the alkylated cyclodextrin; and (d) measuring the chloride level of the alkylated cyclodextrin composition; wherein the chloride level is 0.07% (w/w) or less.
priorityDate 2012-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID297

Total number of triples: 32.