abstract |
The invention relates to a method for extracting and separating cannabidiol, comprising the following steps: 1) crushing: crushing the dried industrial hemp leaves into particles by a grinding and dispersing machine; 2) extracting: using ethanol, petroleum ether or solvent gasoline Reflux the material for single solvent or mixed solvent; 3) Enrichment: carry out macroporous resin chromatography on the industrial hemp stream extract prepared by extraction and concentration, collect and concentrate the eluent in sections to obtain cannabidiol enrichment 4) Separation: the cannabidiol enrichment is subjected to silica gel column chromatography, and the eluent is collected in sections, and the eluent is concentrated, dried and crystallized to obtain cannabidiol; The advantages of convenience, rapidity and low purification cost. |