http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110062763-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110062763-B |
titleOfInvention | Peptide Modulators of Purinergic Receptors |
abstract | The present invention relates to medicine and pharmacology, in particular to bioactive peptides that modulate purinergic signaling. To this end, peptides with the following amino acid sequences were proposed: Gly 1 ‑Tyr 2 ‑Cys 3 ‑Ala 4 ‑Thr 5 ‑Lys 6 ‑Gly 7 ‑Ile 8 ‑Lys 9 ‑Cys 10 ‑Asn 11 ‑Asp 12 ‑Ile 13 ‑His 14 ‑Cys 15 ‑Cys 16 ‑Ser 17 ‑Gly 18 ‑Leu 19 ‑Lys 20 ‑Cys 21 ‑Asp 22 ‑Ser 23 ‑Lys 24 ‑Arg 25 ‑Lys 26 ‑Val 27 ‑Cys 28 ‑Val 29 ‑Lys 30 ‑Gly 31 , or a sequence having at least 90% homology thereto. The peptides of the present invention can be used for the prevention and treatment of diseases mediated by purinergic receptors. The peptides can be used to develop new drugs, such as analgesics, and to study the mechanism of pain, and to identify and test new P2X3 receptor modulators. The peptides of the present invention can be synthesized chemically or produced biotechnologically using the nucleotide sequence of the corresponding gene. |
priorityDate | 2016-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.