http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110054606-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 |
| filingDate | 2019-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110054606-B |
| titleOfInvention | Dihydromyricetin-berberine hydrochloride pharmaceutical co-crystal and preparation method thereof |
| abstract | The invention discloses a dihydromyricetin-berberine hydrochloride pharmaceutical co-crystal, belonging to the technical field of pharmaceutical crystallization. The invention combines dihydromyricetin and berberine hydrochloride together through intermolecular hydrogen bonding to form the dihydromyricetin-berberine hydrochloride pharmaceutical co-crystal. The preparation method is simple and easy to implement and low in cost. The prepared dihydromyricetin-berberine hydrochloride medicine eutectic crystal has a definite structure and no hygroscopicity, the dissolution rates of dihydromyricetin and berberine hydrochloride in water are similar, the dihydromyricetin and the berberine hydrochloride can be synchronously dissolved, and the synergistic enhanced inhibition effect is shown on specific tumor cells. |
| priorityDate | 2019-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.