| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7a780e9de8092c03761d2e939a883c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd683fe7a37129fab8ad027f9fdaaed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5697c37b86bd8cced109a3832dc5f64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07c4ac263cbb01d9a48f76cfb3fd922c |
| publicationDate |
2019-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110051669-A |
| titleOfInvention |
Application of 1,3,3-trimethyl-2-benzimidazopyridine vinylindolium iodide in the preparation of anticancer drugs |
| abstract |
The invention discloses a compound (E)-1,3,3-trimethyl-2-(2-(4-methylbenzo[4,5]imidazo[1,2-a]pyridine-3 -Base) vinyl)-3H-indole-1-onium iodide in the preparation of drugs for inhibiting the growth of A549 lung cancer cells and promoting the apoptosis and autophagy of A549 cells, which can effectively promote the apoptosis and autophagy of A549 cells. The dosage of the drug is 1-10 μM, and the preferred concentration is 5-10 μM. The compound provided by the invention is expected to be used as an effective tool for inhibiting tumor growth, and lays a foundation for the development of non-small cell lung cancer therapeutic drugs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112294956-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112294956-A |
| priorityDate |
2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |