http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110045049-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 |
filingDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110045049-B |
titleOfInvention | Method for simultaneously determining various related substances of montelukast sodium and preparation thereof |
abstract | The invention relates to the technical field of analytical chemistry, in particular to a method for simultaneously measuring montelukast and a plurality of related substances. HPLC determination is adopted, and phenyl bonded silica gel is used as a chromatographic column of the filler; gradient elution was carried out using 0.15% trifluoroacetic acid aqueous solution (a) to 0.15% trifluoroacetic acid acetonitrile solution (B) as a mobile phase. The detection wavelength is 250-260 nm, and the column temperature is 38-42 ℃; the elution flow rate is 1.0-2.0 mL/min. The method is simple and convenient to operate, and can be used for quickly, effectively and accurately measuring the content of the montelukast and various related substances. |
priorityDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.