http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110038009-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 |
| filingDate | 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_515362ee2065e4eaade6d729b46bd70f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c40b2b72ab23a121c415b5d321d20cff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_298eba204e3d7f4f05fd80fe43423cb8 |
| publicationDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110038009-A |
| titleOfInvention | Application of canagliflozin in the preparation of antitumor drugs |
| abstract | The invention provides an application of canagliflozin in the preparation of anti-tumor drugs, especially in the preparation of drugs for treating solid tumors. Studies have shown that canagliflozin can significantly down-regulate the immune checkpoint protein PD-L1 in various tumor cells, and can effectively enhance the killing effect of T cells on tumor cells in the co-incubation model of T cells and tumor cells. , thereby expanding the clinical application of the chemical drug canagliflozin in tumor immunotherapy. The invention provides a new medical use for canagliflozin, and also provides new ideas and potential targets for the development of small molecule drugs based on PD-L1. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112439067-A |
| priorityDate | 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.