| abstract |
The present invention relates to compounds of formula I and their salts and solvates for use as inhibitors of cell division cycle 7 (Cdc7) kinase activity: wherein X, R1, R2 and n are each as defined herein. The present invention also relates to methods for preparing these compounds, to pharmaceutical compositions comprising these compounds, and to the use of these compounds in the treatment of proliferative disorders such as cancer and other diseases or conditions involving Cdc7 kinase activity. |