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filingDate 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110029500-B
titleOfInvention Functionalized oriented fiber for tissue engineering intravascular stent construction and preparation method thereof
abstract The invention relates to a functionalized oriented fiber for constructing a tissue engineering vascular scaffold and a preparation method thereof, wherein a DA/Lys solution is obtained by adding dopamine salt DA and lysine Lys into a buffer solution; immersing the oriented fiber in DA/Lys solution for reaction to obtain the fiber. The invention not only effectively enhances the coating effect of PDA by introducing the active ingredient Lys, but also obviously improves the function of the oriented fiber induced vascular endothelial regeneration after the coating is modified. The PDA/Lys coating method provided by the invention has the advantages of simple process and high efficiency, can effectively overcome the defects of poor biocompatibility, insufficient endothelial regeneration induction function and the like of the polymer-based tissue engineering intravascular stent, and promotes the research and development and clinical application transformation of the functional tissue engineering intravascular stent.
priorityDate 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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