http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110023513-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9822cb33b8c70590a3b36d5f216fd19d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e323a67f866080e721f68576e3811e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_727e52e1ef80fbb6ad41c28a1d04c21a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be4428c12431f95425554140c7687fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12dc2cc12370f6d5ec5ec595f8b97025 |
| publicationDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110023513-A |
| titleOfInvention | Methods for predicting the prognosis of breast cancer patients |
| abstract | The present invention relates to a method for predicting the prognosis of a breast cancer patient, and more particularly, to a method for predicting the prognosis of a breast cancer patient, the method comprising the steps of: (a) measuring tropism in a biological sample obtained from a breast cancer patient Milk lipoprotein subfamily 3 member A2 (BTN3A2) immune-related gene and one or more selected from ubiquitin-conjugating enzyme E2C (UBE2C), topoisomerase 2α (TOP2A), ribonucleotide reductase M2 (RRM2) , the mRNA expression levels of proliferation-related genes in the group consisting of forkhead box M1 (FOXM1) and proliferation marker Ki-67 (MKI67); (b) normalizing the mRNA expression levels measured in step (a); and (c) predicting the prognosis of breast cancer by the combination of the one or more proliferation-related genes and the immune-related genes normalized in step (b), wherein predicting the prognosis of breast cancer results in overexpression of the proliferation-related genes The prognosis is poor when the immune-related genes are overexpressed and the prognosis is good when the immune-related genes are overexpressed. The present invention relates to a method for predicting the prognosis of breast cancer using a gene group shown to be significantly associated with the prognosis of breast cancer, and clinical information, the method of the present invention can more accurately predict the prognosis regarding whether a breast cancer patient will have future metastasis , which can be used for the purpose of providing evidence for future breast cancer treatment directions. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110938698-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113355419-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113355419-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113862363-A |
| priorityDate | 2016-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 158.