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filingDate 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110016232-B
titleOfInvention Preparation method of fish scale collagen composite sponge
abstract The invention discloses a preparation method of fish scale collagen composite sponge, which comprises the steps of crushing fish scales, dissolving, adding an extracting agent, and adjusting pH; filtering, centrifuging, and collecting supernatant; salting out the supernatant, centrifuging, taking the precipitate for redissolving, and adjusting the pH; dialyzing, pre-freezing and freeze-drying to obtain a first collagen sponge; dissolving a base material to obtain a first solution; dissolving the first collagen sponge to obtain a second solution; mixing and stirring the bacteriostatic agent and the emulsifier to obtain a first emulsion; uniformly mixing the first solution and the second solution to obtain a third solution; adding the first emulsion and a plasticizer, and adjusting the pH; and (3) freezing and drying after pre-freezing to obtain the fish scale collagen composite sponge which has the advantages of good mechanical property, antibacterial effect and water resistance.
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