http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110003326-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_776319b2f97a96c3a4ed70c56392013f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-577 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20 |
| filingDate | 2019-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34b8ede5a0a0da9d86540da4bca1d3ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd7c91fcb3cd30d6c37421b03b93d972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a77008310af082e08b615395858b5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d2c399c3b42c197bfb445aad4481fa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3c27e3cb4682c5e02bc7da2d373fc57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d3f60afbed9eb0c7906d23014dd60e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46f96e6bbc4306efda2af7a27d5fadaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b292d7525f6101ba85cdd967a25ca9e |
| publicationDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110003326-A |
| titleOfInvention | Preparation method of hepatitis B virus pre-S1 protein specific antibody and its application |
| abstract | The present invention discloses a method for preparing a hepatitis B virus pre-S1 protein-specific antibody, including mouse monoclonal antibodies against pre-synthetic S1 polypeptide-1 and anti-pre-synthetic S1 polypeptide-2, and preparing by using pre-synthetic S1 fragment polypeptide-1 The artificial antigen prepared with polypeptide-2 was used as the immunogen. The mouse monoclonal antibody against pre-synthesis S1 polypeptide-1 and the mouse monoclonal antibody against pre-synthesis S1 polypeptide-2 were used as coating antibodies, and the anti-HBsAg antibody labeled with horseradish peroxidase was used as the labeling antibody to establish the detection of serum The pre-S1 protein ELISA method has high sensitivity and specificity. On the basis of the existing technology, the applicant team searched for other B cell recognition sites (21aa‑47aa) outside the known B cell recognition site of pre-S1, and prepared specific mouse monoclonal antibodies to enhance the pre-S1 protein The detection rate can provide more accurate reference data for the early screening and prognosis diagnosis of clinical HBV infection. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023066171-A1 |
| priorityDate | 2019-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5862 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419485715 |
Total number of triples: 26.