Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32622955710a511ff5d89f584662fe2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92367512a7327e197920165b674c7aac |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
filingDate |
2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3576d8ddbbbafebb3563649c087c0c1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0069862c4265a6de8f3044bb27c78e09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8591da0b97502d4f78c8012740d9a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19b89da5008cad7f1da9732945d0122d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9be95e24f9d8d7c83ad57426428faa03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33757cdfee2a9014aaae5b88dedf2abb |
publicationDate |
2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110003193-A |
titleOfInvention |
A kind of rivaroxaban that is easy to be pulverized and preparation method thereof |
abstract |
The present invention relates to a method for preparing easily pulverized rivaroxaban. The method includes the steps of adding the crude rivaroxaban into a solvent, heating it up to make it completely dissolved, and then allowing it to stand for cooling and crystallization. By this method, rivaroxaban crystal grains with suitable particle size and uniform particle size can be obtained, which can be easily pulverized. The crystal grains can be directly subjected to one-time jet pulverization to obtain particles with a D 90 of 15 μm or less that meet the formulation requirements. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114886867-A |
priorityDate |
2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |