http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110003047-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-33 |
| filingDate | 2019-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110003047-B |
| titleOfInvention | Method for preparing nitrile by reacting acetone cyanohydrin with alkyl halide |
| abstract | The invention provides a method for preparing nitrile by reacting acetone cyanohydrin with alkyl halide. The invention uses acetone cyanohydrin as a cyaniding reagent, and solves the problems of long reaction time, low yield, strict reaction conditions and the like of the existing preparation method which uses virulent sodium cyanide, potassium cyanide or expensive trimethyl silicon cyanide as a cyanogen source. The method comprises the following steps: dissolving acetone cyanohydrin in a mixed solvent composed of an aprotic high boiling point dipolar solvent and an aprotic low boiling point solvent, adding a catalyst lithium hydroxide, stirring for one hour at 25-50 ℃, adding alkyl halide, continuing to react for 2-3 hours, adding saturated saline solution, washing twice, separating an organic layer, drying, and evaporating the solvent to obtain the nitrile compound. The method for preparing the nitrile compound has the advantages of low reaction toxicity, simple process, easy operation, low production cost and yield of more than 95 percent. |
| priorityDate | 2019-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 158.