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filingDate 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce473e65bbafe074dfb3ff3f340fb37b
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publicationDate 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109999197-A
titleOfInvention Nano-complex, preparation method and its application in the tumour that sound power mediates precisely is treated of cancer target
abstract The invention discloses a kind of nano-complex of cancer target, preparation method and its applications in the tumour that sound power mediates precisely is treated.The nano-complex includes the composite nanoparticle of hyaluronic acid cladding;The preparation method of the composite nanoparticle: the part amino on the surface dendritic macromole PAMAM is become into carboxyl using succinic anhydride, then compound with sensitizer indocyanine green, anti-tumor drug adriamycin and hyaluronic acid, the nano-complex has good sound power anti-tumor effect, sensitizer and anti-tumor drug have good synergy in the treatment, are suitble to noninvasive/minimally invasive oncotherapy.
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