http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109997787-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 |
filingDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109997787-B |
titleOfInvention | Method for breeding rat with non-alcoholic steatohepatitis transformed into hepatocellular carcinoma and application |
abstract | The invention relates to a method for breeding a rat with non-alcoholic steatohepatitis transformed into hepatocellular carcinoma and application thereof, which effectively solve the problem that a stable, reliable and effective modeling rat is provided for the transformation of the non-alcoholic steatohepatitis into the hepatocellular carcinoma, and technical support is provided for animal experiments and new drug research and development of a NASH (liver fibrosis), liver cirrhosis and HCC (liver cancer) generation development mechanism, an adult SD male rat with the weight of 250-300g is fed for 1 week in an adaptive manner, high-fat CDAA feed is fed, diethylnitrosamine is added into drinking water for induction, the mental state and the hair condition of the rat are observed, the food intake and the water intake are measured, and the weight of the rat is measured every week; the method is easy to operate, short in time, stable and effective, and provides modeling and technical support for developing and developing new drugs for treating the conversion of the nonalcoholic steatohepatitis into the hepatocellular carcinoma. |
priorityDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.