http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109991410-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-536 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109991410-B |
| titleOfInvention | A kind of composition containing anti-CD45 monoclonal antibody and using method thereof |
| abstract | The present invention provides a method and application for enriching and identifying circulating tumor cells based on two or more high-affinity anti-CD45 rabbit monoclonal antibodies. Specifically, the present invention provides a composition containing two or more CD45 rabbit monoclonal antibodies, which can recognize different antigenic determinants on the CD45 antigen molecule. The present invention also includes methods of using the composition in combination with anti-CD16 mAb, anti-CD19 mAb and anti-CD235a mAb to isolate leukocytes, enrich and identify circulating tumor cells. The antibody combination of the present invention is a rabbit monoclonal antibody with high affinity and strong specificity, which can better label various leukocyte subtypes, thereby better removing leukocytes, and more efficiently enriching and identifying CTCs without damaging CTCs. cells, so that CTC cells maintain a good natural state and cell morphology. |
| priorityDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.