http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109988212-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 |
filingDate | 2019-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109988212-B |
titleOfInvention | Prednisolone sodium phosphate production method |
abstract | A process for preparing prednisolone sodium phosphate includes such steps as dissolving prednisolone phosphate in the mixture of acetone and water, dropping aqueous solution of sodium hydroxide in tank, controlling temp at 10-25 deg.C, regulating pH value to 9.0-9.5, stirring, filtering, pumping acetone in diluting tank, regulating temp, adding reaction liquid, stirring to educe out a lot of crystals, laying aside for not less than 8 hr, washing with acetone, dry swinging, and drying. The method changes various solvents in the traditional process into a single solvent, solves the bottleneck of diversification of residual solvents in the bulk drugs, shortens half of the drying time, and has the advantages of less than 2.0 percent of total amount of impurities and great quality. |
priorityDate | 2019-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.