http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109988107-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 |
| filingDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109988107-B |
| titleOfInvention | Preparation method of cabozantinib |
| abstract | The present invention relates to a preparation method of cabozantinib. The invention belongs to the field of medicinal chemistry, and the Cabozantinib compound is prepared through two steps. The method of the present invention includes: (1) compound III and compound VI are condensed to prepare compound V; (2) compound V is condensed with p-fluoroaniline to prepare cabozantinib. The preparation method involved in the invention has the characteristics of simple operation, mild reaction conditions, high yield and convenient industrial application. |
| priorityDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.