abstract |
The invention discloses the application of 5α-androsta-3β, 5,6β-triol, its deuterated products or pharmaceutically acceptable salts thereof in preparing a medicine for treating cerebral small vessel disease in patients. The cerebral small vessel disease is preferably cerebral microbleeds. The cerebral microbleeds are spontaneous cerebral microbleeds, drug-related cerebral microbleeds or traumatic cerebral microbleeds. The present invention confirms that 5α-androsta-3β, 5,6β-triol significantly enhances the clearance of extravascular hemoglobin, so that it can be used for the treatment of cerebral small vessel disease. |