| abstract |
The invention discloses a creborone microemulsion composition. The creborone microemulsion composition comprises: by weight percentage, including: 0.5% to 5.0% of creborone, 5% to 20% of an oil phase, 10% to 40% of emulsifier, 5% to 30% of co-emulsifier, 30% to 70% of water, wherein the oil phase is one or more selected from C10-C18 fatty acid monoesters and tricarboxylic acid glycerides The combination, the emulsifier is selected from the Tween series emulsifier. The criborole microemulsion solution of the invention has good stability, has an ideal microemulsion particle size, and can effectively improve the skin permeability of the drug; Penetration and retention can improve the compliance of clinical treatment of allergic dermatitis and have a sustained release effect. |