http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109984998-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate | 2019-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109984998-B |
| titleOfInvention | Preparation method of omeprazole sodium for injection |
| abstract | The invention provides a preparation method of omeprazole sodium for injection, belonging to the field of medical preparations. The omeprazole sodium for injection provided by the invention comprises raw materials of omeprazole sodium, disodium ethylene diamine tetraacetate and water for injection. The preparation method comprises the following steps: sequentially adding disodium ethylene diamine tetraacetate and omeprazole sodium into water for injection, adjusting the pH value by using a sodium hydroxide aqueous solution, adding activated carbon for adsorption to remove a heat source, adding the rest water for injection, and filtering to remove the activated carbon or filtering the heat source by adopting an ultrafiltration membrane to obtain a semi-finished product; detecting the content and pH value of the semi-finished product, sterilizing and filtering after the semi-finished product is qualified, quantitatively filling, and freeze-drying to obtain a freeze-dried product; and (4) corking the freeze-dried product, capping, inspecting the finished product, labeling and packaging to obtain the finished product. The invention also discloses application of the omeprazole sodium for injection in preventing aspiration pneumonia caused by gastric acid reflux for patients with indications of general anesthesia or postoperation and asthenia coma. |
| priorityDate | 2019-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.