abstract |
The invention discloses a synthesis method of a 3,3 '-disubstituted-2-indolone compound, which takes an aniline compound as a raw material to directly prepare the 3, 3' -disubstituted-2-indolone compound by reacting with a bromoethyl acetate compound. Has the advantages of economy, convenience, easily obtained raw material sources, wide reaction substrate application range and high target product yield. |