http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109942655-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 2019-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109942655-B |
| titleOfInvention | Continuous crystallization method of erythromycin thiocyanate crude product |
| abstract | The invention relates to the field of biological pharmacy, in particular to a continuous crystallization method of erythromycin thiocyanate. Continuously mixing fermented erythromycin filtrate with a sodium thiocyanate solution, and pumping the mixture into a reaction tank through a circulating pump to realize reciprocating circulation; and when the volume of the reaction tank reaches 65-75% of the volume of the reaction tank, discharging, wherein the discharging crystal slurry rate is the same as the feeding rate of the fermented erythromycin filtrate, and the discharging crystal slurry enters a crystallization buffer tank for crystal growing to finish the continuous crystallization of the crude erythromycin thiocyanate. The continuous crystallization system provides a relatively stable and consistent crystal nucleus and crystal growth process for the formation of the erythromycin thiocyanate coarse crystals by utilizing relatively stable supersaturation, so that the components of the erythromycin thiocyanate coarse crystals are more stable finally. |
| priorityDate | 2019-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.