http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109939269-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 |
filingDate | 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109939269-B |
titleOfInvention | Surface modification method of intravascular stent material, intravascular stent material obtained after modification and application of intravascular stent material |
abstract | A surface modification method of a vascular stent material, a vascular stent material obtained after modification and application thereof belong to the technical field of cardiovascular stent material surface modification. The first part is the deposition of dopamine (PDA) polymer film on the surface of the material. Firstly, the dopamine can initiate mild self-polymerization-crosslinking reaction under the aerobic and alkaline conditions, and can generate chelation and self-polymerization reaction with materials to form a stable dopamine polymer film. The second part is the modification of the exosomes on the surface of the PDA film. And immersing the material deposited with the PDA film in the exosome suspension, and reacting for a period of time to obtain the polydopamine/exosome modification layer. Due to the positive charge property of the exosome, the exosome can generate electrostatic interaction with the PDA film with negative charge, so that the constructed polydopamine/exosome modification layer can be stably combined with the material. |
priorityDate | 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.