http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109929036-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_598a905b1081c2f3e1a0bb3bd85f23c1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41ecad4c0db8744a02712291beea2fd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_508316ad91cea0b361c57e35f8bb7418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198979533db65e990947ad13de720677 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c4796bba34dd7fcc3e5469161da1c17 |
| publicationDate | 2019-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109929036-A |
| titleOfInvention | A kind of antibody screening method that epitope is special and the antibody screened |
| abstract | A kind of antibody screening method that epitope is special, it is low to solve the problems, such as to have in screening of phage antibody library technology medicative functional antibodies screening efficiency, include the steps that being screened with function epitope peptide and living cells screens；It additionally provides and screens a kind of phage displaying antibody library complete anti-PD-1 monoclonal antibody of source of people obtained with this method, for specific functional epitope, PD-1 and the combination of its ligand can effectively be blocked, and have the characteristics that affinity is high, EC50 is low, therapeutic effect can be generated to animal model under low dosage.The present invention substantially increases the screening efficiency of functional antibodies, and provides a kind of immunotherapy medicaments of potential safer economy for malignant tumour, immunological diseases patient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110656092-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021043337-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021197212-A1 |
| priorityDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 440.