| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf0b2517d794e4715d29bfcb609ce7cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-643
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
| filingDate |
2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6ceb28d0f7323696ea55de391ef13a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c99c2ff6a4f0cfda0ea960e30fbb35b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c71c8ae0132c5640e17d31ec38d3ede
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9344cd300d11b7e58009c85b8d058db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3f2f8895958040dbb40713fba64755a |
| publicationDate |
2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109922824-A |
| titleOfInvention |
Truncated von Willebrand factor polypeptides for the treatment of hemophilia |
| abstract |
The present invention relates to a polypeptide comprising a truncated von Willebrand factor (VWF) and a half-life extending moiety for use in the treatment of a coagulation disorder comprising administering the polypeptide to a subject suffering from a coagulation disorder and having endogenous factor VIII (FVIII), wherein the subject has a reduced level of endogenous FVIII activity relative to the activity level of FVIII in normal human plasma (NHP) prior to treatment with the polypeptide, provided that The activity level of endogenous FVIII in said subject is at least 0.5% of the activity level of endogenous FVIII in normal human plasma (NHP), wherein the polypeptide is capable of binding endogenous FVIII, and wherein after administration of said polypeptide Endogenous FVIII levels increased. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113862301-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114072420-A |
| priorityDate |
2016-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |