http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109912418-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-333 |
| filingDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109912418-B |
| titleOfInvention | Preparation method of trans-4-phenyl-3-ethyl crotonate compound |
| abstract | The invention belongs to the technical field of pharmaceutical and chemical intermediates and related chemistry, and relates to a preparation method of a trans-4-phenyl-3-ethyl crotonate compound, wherein 2-phenylcyclopropane-1, 1-diethyl dicarboxylate derivative is used as a raw material, an isomerization/elimination reaction is carried out under the action of Lewis acid serving as an accelerator, and the reaction is carried out in an organic solvent at 130 ℃ for 24 hours to obtain the trans-4-phenyl-3-ethyl crotonate compound. The method has the advantages of simple and convenient operation, cheap and easily obtained starting raw materials, no byproduct generation, possibility of realizing industrialization and obtaining the trans-4-phenyl-3-ethyl crotonate compound with higher yield; the trans-4-phenyl-3-ethyl crotonate compound synthesized by the method can be further functionalized to obtain various compounds, and is applied to development and research of natural products, functional materials and fine chemicals. |
| priorityDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.