http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109908362-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
| filingDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a670968971d9e7ec21874b7b14ba4e0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fc9310b4d656b25d8b1c10c822f4fae |
| publicationDate | 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109908362-A |
| titleOfInvention | A biotin-targeted modified photosensitizer and quercetin nano-drug delivery system |
| abstract | The present disclosure relates to the technical field of nano-drug delivery systems, in particular to a biotin-targeted modified photosensitizer and a quercetin nano-drug delivery system. In view of the poor water solubility and low bioavailability of photochemotherapy agents and quercetin in the prior art, as well as the defects of tumor tolerance brought by photosensitizers. The present disclosure is the first time to use biotin-modified IR780 and quercetin to co-assemble to form a nano-system, which not only solves the shortcomings of quercetin and IR780, such as insoluble in water and low bioavailability, but also overcomes the tumor tolerance caused by photosensitizers. sex. The prepared B780/Qu NPs nano-assemblies, with a particle size of 130 nm, conform to the size range of tumor penetration and retention effects, and have good passive and active targeting. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112933229-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111214656-A |
| priorityDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.