http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109908347-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109908347-B |
titleOfInvention | Method for improving killing efficiency of low-temperature plasma on cancer cells by targeted protective autophagy |
abstract | A method for improving the killing efficiency of low-temperature plasma on cancer cells by targeted protective autophagy relates to the field of biological medicine. The invention provides an application of a cell autophagy inhibitor in preparing a medicament for assisting low-temperature plasma in treating cancer or improving the killing effect of cancer cells of low-temperature plasma. The invention discovers that the low-temperature plasma can effectively induce the apoptosis of cancer cells and kill cancer cells such as non-small cell lung cancer, breast cancer and the like; the low-temperature plasma induces apoptosis and simultaneously initiates the generation of protective cell autophagy; the protective cell autophagy is taken as a target, and the autophagy inhibitor is used for inhibiting the cell autophagy, so that the killing efficiency of low-temperature plasma on cancer cells is effectively improved. The method provided by the invention can obviously improve the killing efficiency of the low-temperature plasma on cancer cells, and provides a new idea for the application of the subsequent low-temperature plasma in clinical treatment and the improvement of the curative effect of the low-temperature plasma. |
priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.