http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109908110-B

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filingDate 2019-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109908110-B
titleOfInvention A double-layer composite drug-loaded adhesive patch and its preparation method and application
abstract The invention discloses a double-layer composite drug-loaded adhesive patch and its preparation method and application, belonging to the technical field of medical and biomedical materials. After mixing the burst-release agent and the sustained-release agent with polymers, use electrospinning equipment to prepare the burst-release agent layer and the sustained-release agent layer, and then conform to the adhesive film to obtain a double-layer composite drug-loaded adhesive patch . When in use, the burst-release agent layer and the slow-release agent layer can be loaded with different types of drugs to form a gradient release to achieve the best therapeutic effect. As a carrier, the nanofibrous membrane has the advantages of high specific surface area, high porosity, moisture permeability, and fine fiber diameter, which can increase the drug load. High porosity is conducive to cell growth and proliferation, and promotes rapid wound healing. , Moisture-permeable and breathable can simulate the natural environment of the mucous membrane or skin, which is conducive to the growth of new cells on the wound surface, and the fine fiber diameter can provide more growth sites for cells, which can accelerate wound repair.
priorityDate 2019-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 39.