http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109897827-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109897827-B |
titleOfInvention | Construction method and application of zebra fish model for researching stress particles |
abstract | The invention relates to a construction method of a zebra fish model for researching stress particles and application of the zebra fish model. Specifically, the invention establishes a visual in-vivo model for observing SG formation and change in real time, wherein the model is a zebra fish model in which a fluorescent gene is inserted in the genome of the cell in an endogenous stress particle-associated gene (such as a G3BP1 gene) or at two ends of a coding region, and the fluorescent gene is inserted in a frame unchanged manner. The zebra fish in-vivo tool can promote the research on SG to an in-vivo model, is used for researching the influence of various behaviors, stimuli or physiological changes on the formation of stress particles, and can also be used for screening medicaments capable of regulating the formation and the change of the stress particles in vivo. |
priorityDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.