http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109897105-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109897105-B |
titleOfInvention | Monoclonal antibody of EV71 virus, preparation method and detection test strip thereof |
abstract | The invention provides a monoclonal antibody of EV71 virus, a preparation method thereof and a detection test strip thereof. The monoclonal antibody of EV71 virus comprises a heavy chain variable region and a light chain variable region, wherein the DNA sequence of the heavy chain variable region of the monoclonal antibody is shown as SEQ ID NO. 1, and the DNA sequence of the light chain variable region is shown as SEQ ID NO. 2. The monoclonal antibody which can widely recognize three capsid proteins of viruses VP1, VP2 and VP3 is obtained; the invention obtains the gold-labeled antibody with stable property after being labeled with colloidal gold, successfully expresses Protein A which can be combined with the Fc end of the antibody, and provides conditions for the preparation of test paper; the test strip capable of rapidly and effectively detecting the presence of the EV71 virus is obtained. The method provides rapid and effective guidance for the diagnosis of the hand-foot-and-mouth disease pathogens and the establishment of clinical treatment methods. The EV71 rapid detection test strip provides a powerful basis for prevention, control and treatment of hand-foot-and-mouth diseases. |
priorityDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.