http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109884224-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109884224-B |
| titleOfInvention | Carbazochrome sodium sulfonate and method for measuring content of semicarbazide hydrochloride in preparation thereof |
| abstract | The invention provides a method for preparing detection samples of carbazochrome sodium sulfonate and a preparation thereof, which comprises the following steps: respectively taking a sample to be detected, a semicarbazide hydrochloride reference substance and a blank, adding water and methanol to dissolve, adjusting the pH value to be 2.0-8.0, shaking up, adding a 2-naphthaldehyde solution, adding water to a constant volume, shaking up, reacting at room temperature for 1-5 h, filtering, adding n-hexane into a subsequent filtrate for extraction, centrifuging, taking a bottom layer aqueous solution for repeated extraction, and centrifuging to obtain the composition. The invention also provides a method for measuring the content of semicarbazide hydrochloride in the carbazochrome sodium sulfonate and the preparation thereof, which considers the measurement of the content of semicarbazide hydrochloride in the carbazochrome sodium sulfonate preparation with different dosage forms, has better universality and specificity, high sensitivity, convenient operation and moderate analysis time, provides effective guarantee for the quality control of the content of semicarbazide hydrochloride in the carbazochrome sodium sulfonate and the preparation thereof, ensures the medication safety and has good application prospect. |
| priorityDate | 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.