http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109879923-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e233a4bafba614d774a51c65843a059
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
filingDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb9240ad9ac100e4e98db41338c25f13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04c084fc7a0728f9a891b50f81be8e4b
publicationDate 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109879923-A
titleOfInvention The separation purifying technique of high-purity natural ursodesoxycholic acid can be prepared
abstract The invention belongs to technical field of pharmaceutical biotechnology, and the separation purifying technique of high-purity natural ursodesoxycholic acid can be prepared more particularly to one kind.High-purity natural ursodesoxycholic acid isolates and purifies gained by bear gall powder prepared by drain-out bear gall, and high-efficient liquid phase color spectral purity is not less than 98%.Preparation method is: isolating and purifying the Tauro ursodesoxy cholic acid that preparation purity is not less than 90% using cation exchange medium first; then Tauro ursodesoxy cholic acid is thoroughly hydrolyzed to ursodesoxycholic acid and taurine under alkaline condition, silica gel adsorption chromatography technology is reapplied and isolates and purifies the ursodesoxycholic acid that preparation purity is not less than 98%.Natural ursodesoxycholic acid produced by the present invention has treatment primary biliary cirrhosis and primary sclerotic cholangitis effect.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113480589-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113480589-A
priorityDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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