http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109879847-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_052a9db42e32a622fd7a5b606b68799e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-30 |
| filingDate | 2019-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c21c736008604d55ef15174188a4f38c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2eb1174373455e012226865fe618387 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8c7beb0dfbd49dccfde37b4a5a2d3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a844425c716743a8811a84b810ba8f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_867aa676e651b4a465ba641240a799a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2875b676e5d947103dc0590e56129f55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d29fcebdd8d03bd974782e7f4a3219ff |
| publicationDate | 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109879847-A |
| titleOfInvention | Deuterated flavone compound and preparation method thereof |
| abstract | The present invention relates to a kind of deuterated flavone compounds and preparation method thereof, the following steps are included: flavone compound, alkali and heavy water are mixed, reaction obtains deuterated flavone compound sodium salt under 90 DEG C of conditions above in inert gas environment, then organic acid acidification is added, obtains deuterated flavone compound；Wherein, flavone compound is at least one of baicalein, scutelloside, luteolin, apiolin, Quercetin, Kaempferol, Isorhamnetin, hesperetin, Puerarin and daidzein, and alkali is deuterium sodium oxide molybdena and/or sodium hydroxide.Above-mentioned synthetic method provided by the invention is simple and efficient, which can react under 90 DEG C of conditions above, and condition is more mild, yield is higher simultaneously, and at least up to 40%, operating process is simple, catalyst is easily obtained, and production cost is low, can be used for large-scale industrial production. |
| priorityDate | 2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.