http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109876196-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 |
filingDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109876196-B |
titleOfInvention | Silk fibroin bionic porous scaffold and preparation method and application thereof |
abstract | The invention discloses a preparation method of a silk fibroin bionic porous scaffold, which comprises the following steps: dissolving silk fibroin in an organic solvent to prepare a silk fibroin solution, and then adding acetone to form a gel solution; adding a pore-foaming agent into the obtained gel-like solution, uniformly mixing, and then transferring into supercritical drying equipment for supercritical drying treatment; and soaking the obtained product in alcohol, and then drying to obtain the silk fibroin bionic porous scaffold. The silk fibroin bionic porous scaffold has coexisting macroporous and microporous characteristics, high porosity and a rough nanofiber mesh-like interwoven structure allowing cell adhesion, can simulate an extracellular matrix microenvironment and is beneficial to promoting cell adhesion and proliferation; the related preparation process is green and environment-friendly, high temperature is not used, and the problems of organic solvent residue and the like can be avoided; the obtained silk fibroin bionic porous scaffold can be widely applied to the fields of artificial skin scaffolds, artificial nerve scaffolds, bone tissue engineering scaffolds and the like. |
priorityDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.