http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109856303-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-38 |
| filingDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109856303-B |
| titleOfInvention | High-sensitivity analysis method for genotoxic impurities in pantoprazole sodium |
| abstract | The invention discloses a high-sensitivity analysis method of genotoxic impurity 2-chloromethyl-3, 4-dimethoxypyridine hydrochloride (CMDP) in pantoprazole sodium. The method adopts a high performance liquid chromatography-mass spectrometry combined analysis method, uses a mixed solution of ammonium bicarbonate solution and acetonitrile to dilute a sample, uses volatile carbonate solution and acetonitrile as mobile phases, has detection limit and quantification limit of 0.2ppm and 0.6ppm respectively, can separate and detect the CMDP impurity more efficiently, and has the advantages of strong specificity, high sensitivity, simplicity, rapidness and low cost. |
| priorityDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.