http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109851674-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109851674-B |
| titleOfInvention | Preparation and purification method of recombinant human serum albumin/growth hormone fusion protein for treating children's dwarf syndrome |
| abstract | The invention discloses a recombinant human serum albumin/growth hormone fusion protein, a preparation and purification method of the recombinant fusion protein and application of the recombinant fusion protein in preparing a medicament for treating children short stature. The amino acid sequence of the recombinant human serum albumin/growth hormone fusion protein is SEQ ID NO.1, and the nucleic acid sequence is SEQ ID NO. 2. The preparation process of the invention obtains high-density expression recombinant fusion protein by constructing expression yeast engineering bacteria, and obtains the recombinant human serum albumin/growth hormone fusion protein which can be clinically used by a purification process. The recombinant human serum albumin/growth hormone fusion protein obtained by the preparation and purification method is an innovative medicine structure for treating the childhood dwarf syndrome, achieves the long-acting property of once administration for two weeks, is more suitable for the requirements of children on medication, and has better curative effect, less administration frequency and lower production cost. |
| priorityDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 557.