http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109851512-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C247-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-20 |
filingDate | 2019-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109851512-B |
titleOfInvention | Muscone derivative, preparation method and application thereof |
abstract | The invention discloses a muscone derivative, a preparation method and application thereof, and belongs to the technical field of biological materials. The muscone derivative has structures shown as a formula (A) and a formula (B) and pharmaceutically acceptable salts of the structures, the invention also discloses a preparation method and application of the musk ketone derivative. The musk ketone derivative of the invention is easy to form hydrochloride, and can improve the solubility of the musk ketone derivative; secondly, the active group amino on the structure can be connected to a carrier material through chemical reaction, thirdly, the active group amino can be used as a target head to be modified on the surface of the carrier material, and the drug-loaded nano delivery system can be promoted to enter the brain only by modifying with little dose; fourthly, the method can be used for preparing the musk ketone phospholipid compound, and the musk ketone phospholipid compound has good biocompatibility, has the advantage of promoting a delivery system to penetrate a blood brain barrier, and can be used for preparing brain-targeted delivery medicaments. |
priorityDate | 2019-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.