abstract |
Some embodiments described herein provide multi-component compositions and methods for their pharmaceutical and cosmetic uses, comprising a combination of an aliphatic anionic compound, an oxidizing compound, and a buffer system. Sources of fluoride ions and other carriers are optional ingredients. The aliphatic anionic compound and the oxidative compound work together to protect the oxidative compound from degradation before and during use, and to enhance the efficacy of the composition, in the presence or absence of a source of fluoride ions. In addition to achieving higher stability, the combined effect of aliphatic anionic compounds, oxidizing compounds and fluoride ion sources can enhance fluoride absorption, improve enamel protection by enhancing remineralization and reduce demineralization, and increase plaque removal, Reduced regrowth of dental plaque polymicrobial films, greater availability of chlorite ions and efficient oxidation of salivary biomolecules. |