| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c7c6b46c3f886e76f7ae13540f485b5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0678
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-39 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0786
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2017-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20145853e1cbc3bc037efc792ee32752 |
| publicationDate |
2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109843317-A |
| titleOfInvention |
Compositions and methods for reprogramming adult cells by stemness of platelet-rich fraction of platelet-like cell-containing blood in humans |
| abstract |
The invention provides methods for functionally reprogramming adult cells into immature cell types expressing one or more embryonic biomarkers using a platelet-rich fraction, the platelet-rich fraction comprising platelet-like cells from umbilical cord blood or peripheral blood, and in vitro expanded immature cell types under culture conditions that generate a population of insulin-producing cells that express human beta cell-specific transcription factors and are Functionally equivalent to human pancreatic beta cells. Further provided is a pharmaceutical composition comprising a cell product comprising a therapeutic amount of a population of insulin-producing cells, wherein the population of insulin-producing cells expresses a human beta cell-specific transcription factor and is functionally equivalent to human pancreatic beta cells, and A method for treating a subject subject with a disease characterized by hyperglycemia with a pharmaceutical composition. |
| priorityDate |
2016-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |