http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109836522-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F210-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-42 |
| filingDate | 2019-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109836522-B |
| titleOfInvention | A kind of zwitterionic polymer grafted nanomedia with weakly hydrophobic side chain and method for preparing and immobilizing enzyme |
| abstract | The invention relates to a zwitterionic polymer grafted nanomedia with weakly hydrophobic side chains and a method for preparing and immobilizing enzymes; the invention selects poly(isobutylene-alt-maleic anhydride) and N,N-dimethylformaldehyde A zwitterionic polymer (pID) with a weakly hydrophobic side chain, which is the linking product of ethylenediamine, was used as a modifier, and the carbodiimide method was used to carry out a grafting reaction on the surface of silica nanoparticles (SNPs) to obtain a The zwitterionic polymer with weakly hydrophobic side chains is grafted to the nano-medium SNPs-pID; then the SNPs-pID is used as a carrier, and the enzyme is covalently combined with the polymer on the surface of the carrier to prepare the immobilized enzyme. The nanometer medium prepared by the invention has good biocompatibility and is helpful for stabilizing the structure of the enzyme protein. The immobilized enzyme used as a carrier has high catalytic activity and significantly enhanced stability, and the preparation process is simple and easy to implement and has low toxicity. , it will have broad application prospects in the field of enzyme catalysis. |
| priorityDate | 2019-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.