http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109836475-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 |
| filingDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109836475-B |
| titleOfInvention | Method for converting ramipril impurity D into ramipril |
| abstract | The invention belongs to the technical field of medicine synthesis, and particularly discloses a method for converting ramipril impurity D into ramipril, wherein acylated amino acid hydrolase is used as a catalyst, so that the ramipril impurity D is converted into the ramipril, the reaction molar yield is over 90%, the purity is over 99.9%, and excellent substrate adaptability is shown. Meanwhile, an efficient way is provided for specifically hydrolyzing small molecular compounds containing peptide bonds. The method has simple process and easy operation, and is very suitable for industrial application. |
| priorityDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.