http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109836458-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
filingDate 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d3c21b248e832e3705db8c484bc387
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d24af74c7c18c4ac87a9159a2743b73b
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publicationDate 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109836458-A
titleOfInvention A kind of Aldoforwe ester isomer impurities and the preparation method and application thereof
abstract The invention discloses a kind of Aldoforwe ester isomer impurities 1 and preparation method thereof, it is that be starting material using adenine and ethylene carbonate synthesize Aldoforwe ester isomer impurities 1 through multistep reactions such as alkylation, condensation, hydrolysis, esterifications, and through MS and 1 H NMR etc. has carried out structural identification.Aldoforwe ester isomer impurities 1 are different from having Aldoforwe ester impurity reported in the literature, its isomer for belonging to Aldoforwe ester, structure is similar with Aldoforwe ester principal component, its physicochemical property may also be similar compared with Aldoforwe ester principal component, a possibility that processing step is larger with respect to other impurities difficulty to its Scavenging activity, remains in Aldoforwe ester finished product is also larger.Therefore the study on the synthesis of the isomer impurities of Aldoforwe ester and its intermediate is of great significance for the quality control of Aldoforwe ester.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111007168-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111007168-A
priorityDate 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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