http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109836420-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109836420-B |
| titleOfInvention | Compound, preparation method thereof and application of compound as fluorescent probe |
| abstract | The application discloses a compound I, a preparation method thereof and application of the compound I as a fluorescent probe. The compound I has near-infrared excitation/emission, wherein the excitation wavelength range is 500nm-750nm, the excitation is carried out at the maximum absorption wavelength of 670nm, and the emission wavelength is 700-810 nm; in addition, the compound I also has ultrahigh sensitivity response to PGP-1 enzyme at lambda ex / em The limit of detection of PGP-1 enzyme was 0.18ng/mL at 670/700 nm. The compound I is used as a fluorescent probe, realizes the detection and fluorescence imaging of PGP-1 in vivo for the first time, can realize the detection and fluorescence imaging of PGP-1 in vitro, cells and in vivo, and can perform detection analysis and imaging on all cells and tissues with inflammatory reaction and canceration. |
| priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 851.