http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109824764-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89f3efb8583f1229b9a555a3776c89ba |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 |
| filingDate | 2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a44b0d4da88996b2fe1ac597d6399952 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1bd02c754bf05789ac6e7072fd296bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a93ced7f7ceded5a309ae1eb084fcf |
| publicationDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109824764-A |
| titleOfInvention | A simple method for synthesizing ubiquitin probe Ub-Rho110-Gly |
| abstract | The invention discloses a simple method for synthesizing the ubiquitin probe Ub-Rho110-Gly. First, the ubiquitin hydrazide Ub(1-75)-NHNH 2 is prepared by using the N-S acyl transfer semi-synthesis strategy, and based on the hydrazide method It was further converted into the ubiquitin thioester Ub(1-75)-Mesna, and then the ubiquitin probe Ub-Rho110-Gly was obtained by direct aminolysis. The method of the invention has the characteristics of high preparation yield, high synthesis purity (about 30-40 mg of Ub(1-75)-NHNH 2 can be obtained per 1 L of culture medium after freeze-drying), simple operation and mass preparation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110294793-A |
| priorityDate | 2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.