http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109824662-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_545a2a4d3ba8cdbca206e29416d3b64b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2019-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_990fb54c7e80ea326f74bc9f93827aa6 |
| publicationDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109824662-A |
| titleOfInvention | A kind of quinine compound and preparation method thereof |
| abstract | The invention relates to a quinine compound and a preparation method thereof, in particular to a compound (I) having the following structure and a preparation method thereof. The steps are: 2,2-diphenyloxirane and 3-quinine The alcohol is reacted in an organic solvent under the action of a strong base to obtain 2-(3-quinyloxy)-1,1-diphenylethanol; the (1) step product is combined with 2,2-diphenyloxirane again Alkane reacts under the action of strong base in an organic solvent to obtain 2-[2-(3-quinyloxy)-1,1-diphenylethoxy]-1,1-diphenylethanol; (2) The step product is dissolved in an organic solvent, passed into hydrogen chloride gas, cooled and crystallized to obtain 3-[2-cyclopentyl-2-phenyl-2-(2-cyclopentyl-2-hydroxyl-2-phenyl-ethyl oxy)ethoxy]quinuclidine hydrochloride. |
| priorityDate | 2019-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.