http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109824640-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-12 |
| filingDate | 2019-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109824640-B |
| titleOfInvention | Coumarin compound and pharmaceutical composition, preparation method and application thereof |
| abstract | The invention discloses a coumarin compound with BRD4 protein inhibition effect, which comprises the following components: a compound having a structure represented by the following formula (I) and a pharmaceutically acceptable salt thereof; the compound containing the coumarin parent nucleus and the brand new structure can inhibit BRD4 protein to different degrees, can be used for preparing BRD4 protein inhibitors, and can also be used for preventing and treating diseases related to the activity of BRD4 protein, and the related diseases have a great variety, so that the application range of the compound is wide. The invention also discloses a preparation method of the coumarin compound, which has the advantages of wide raw material source, simple operation, mild condition and low cost, and is very suitable for industrial large-scale production. |
| priorityDate | 2019-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.